Applying the Striking Advancements in Cryo EM to Discovery Research

July 9, 2019 8:00 AM - 10:00 AM

MassBio, 300 Technology Square 8th Fl, Cambridge, MA 02139

Add to Calendar 7/9/2019 8:00:00 AM 7/9/2019 10:00:00 AM Applying the Striking Advancements in Cryo EM to Discovery Research

Biopharma has begun to exploit the new capability of cryo electron microscopy to deliver high resolution protein structures for non-crystallizable proteins. Drug and biologics design projects are benefitting from this new technology that comprises complex and expensive facilities. How are Massachusetts practitioners navigating this space and implementing workflows?

Join us for this Drug Discovery working group forum exploring where the enterprise of applying cryo electron microscopy stands and what different approaches and experiences there are.

  • Case studies of cryo-EM implementation and project impact by local biotech and biopharma
  • Strategies and approaches taken - outsourcing, in-house, or mixed models
  • Discussion on the current and future potential of cryo-EM in industry
  • Local Cryo EM university core facilities will be invited to join this interactive discussion
 MassBio, 300 Technology Square 8th Fl, Cambridge, MA 02139
Scientific Director, Sanofi
Hans-Peter Biemann began his biotech career in the 1990s during the initiation of Genzyme's small molecule discovery enterprise. In that decade he originated multiple Genzyme programs, comprising design of productive lead ID strategies using target-based and phenotypic primary screens. Fragment-based and structure-based drug design were more recently enabled by his work and applied in multiple disease areas during the current decade when Genzyme joined Sanofi. His current responsibilities include leading Sanofi's North America structural biology group that supports drug discovery and other functions. He trained in cellular signal transduction and protein structure-function and Harvard (Ph.D.) and U.C. Berkeley.