Embracing Change: How Innovators are Advancing Continuous Biopharma Manufacturing

June 12, 2019 8:00 AM - 10:00 AM

MassBio, 300 Technology Square 8th Fl, Cambridge, MA 02139

Building on the realization of continuous manufacturing for commercial small molecule APIs and drug products, the dominos finally are beginning to fall into place for the advancement of integrated processes for biopharmaceutical applications. Regulatory engagement, novel and disruptive process and measurement technologies, and simple economics all are playing key roles in recent progress. This forum, intended for a broad audience of scientists and business leaders across the MassBio community, will explore how each of these change-agents are helping to overcome long-time deterrents and, in doing so, have the potential for improving manufacturing reliability and product quality – thereby reducing risks to patients and other key stakeholders.

Discussion and Key Take-Aways Will Include:

  1. Establishing the business case for continuous biomanufacturing – when and for what applications does it make sense?
  2. Applying single-use technologies, automation, and other innovations to enable success in downstream continuous processing.
  3. Advances in measurement and process analytical technologies to enable process/product understanding in alignment with regulatory guidances.
Forum Bonus: We will have extended networking from 10am-11am so you can meet with Bio-Process Systems Alliance, BioPhorum and NIIMBL organizations to learn how they work with industry to accelerate manufacturing innovation as well as find out about their latest white papers, reports and events.
Edwin R. Gilliland Professor, Faculty Research Officer
Richard D. Braatz is the Edwin R. Gilliland Professor at the Massachusetts Institute of Technology (MIT) where he does research in control theory and its application to biomedical, pharmaceutical, energy, and nanotechnology systems. He received MS and PhD degrees from the California Institute of Technology and was the Millennium Chair and Professor at the University of Illinois at Urbana-Champaign and a Visiting Scholar at Harvard University before moving to MIT. He has consulted or collaborated with more than 20 companies including IBM, United Technologies Corporation, Novartis, and Abbott Laboratories. Honors include the Donald P. Eckman Award from the American Automatic Control Council, the Curtis W. McGraw Research Award from the Engineering Research Council, the Antonio Ruberti Young Researcher Prize, and the IEEE Control Systems Society Transition to Practice Award. He is a Fellow of IEEE, IFAC, and the American Association for the Advancement of Science.